2018 / International Journal of Mycobacteriology 7(4):368
Background: The current research aims to isolate pyruvate kinase (Pyk) gene from Mycobacterium tuberculosis and expression of the gene (Rv1617)… Continue reading Expression, purification, and characterization of pyruvate kinase from Mycobacterium tuberculosis: A key allosteric regulatory enzyme
2020 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Volume 241, 5 November 2020, 118645
Beer-Lambert-Bouguer law is for a limiting case and, therefore, it is not useful to describe the relationship between absorption signal… Continue reading Simultaneous absorption of UV–vis and circular dichroism to measure enantiomeric concentrations of praziquantel under nonlinear conditions
2020 / Scientific Reports volume 10, Article number: 11276 (2020)
Lipopolysaccharide (LPS) is a critical component of the outer membrane (OM) of many Gram-negative bacteria. LPS is translocated to the… Continue reading Mutational analysis of the essential lipopolysaccharide-transport protein LptH of Pseudomonas aeruginosa to uncover critical oligomerization sites
2020 / Fitoterapia Volume 144, July 2020, 104605
Toosendansins E-I (1–5), five new limonoids together with nine known limonids(6–14), were isolated and identified from the fruits of Melia… Continue reading New meliacarpin-type (C-seco) and C-ring intact limonoids from the fruits of Melia toosendan
2020 / Nature Communications volume 11, Article number: 3907 (2020)
Nucleic acids can fold into G-quadruplex (G4) structures that can fine-tune biological processes. Proteins are required to recognize G4 structures… Continue reading Zuo1 supports G4 structure formation and directs repair toward nucleotide excision repair
2020 / Scientific Reports volume 10, Article number: 13306 (2020)
Zika virus has recently emerged as an important human pathogen that has spread to more than 60 countries. Infection of… Continue reading Identification of the viral RNA promoter stem loop A (SLA)-binding site on Zika virus polymerase NS5
2020 / Scientific Reports volume 10, Article number: 13621 (2020)
Defects of vitamin B6 metabolism are responsible for severe neurological disorders, such as pyridoxamine 5′-phosphate oxidase deficiency (PNPOD; OMIM: 610090),… Continue reading Molecular characterization of pyridoxine 5′-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy
2020 / Communications Chemistry volume 3, Article number: 100 (2020)
A topic that has attracted considerable interest in recent years is the possibility to perform thermodynamic studies of proteins directly… Continue reading Quantifying the thermodynamics of protein unfolding using 2D NMR spectroscopy
2020 / Nature Communications volume 11, Article number: 3944 (2020)
Triacylglycerols (TG) are synthesized at the endoplasmic reticulum (ER) bilayer and packaged into organelles called lipid droplets (LDs). LDs are… Continue reading Triacylglycerols sequester monotopic membrane proteins to lipid droplets
2020 / Communications Chemistry volume 3, Article number: 111 (2020)
Detection of nucleic acids is crucial to the study of their basic properties and consequently to applying this knowledge to… Continue reading Optical and theoretical study of strand recognition by nucleic acid probes
2020 / International Journal of Biological Macromolecules
This study investigates conformational aspects of ulvans (F2) and their polycarboxyl derivatives obtained through periodate–chlorite oxidation (C3) followed by DEAE-Sephacel… Continue reading Conformational analysis of ulvans from Ulva fasciata and their anticoagulant polycarboxylic derivatives
2020 / Biochimica et Biophysica Acta (BBA) - Biomembranes
Membrane active peptides (MAPs) have gained wide interest due to their far reaching applications in drug discovery and drug delivery.… Continue reading Discovery and mechanistic characterization of a structurally-unique membrane active peptide
2020 / Scientific Reports
The function of IM30 (also known as Vipp1) is linked to protection and/or remodeling of the thylakoid membrane system in chloroplasts… Continue reading GTP hydrolysis by Synechocystis IM30 does not decisively affect its membrane remodeling activity
2020 / New Journal of Chemistry
Self-assembly is one of the most vital molecular behaviors of natural collagen, which plays a prominent role in the design… Continue reading A quantum dot-based fluorescence sensing platform for the efficient and sensitive monitoring of collagen self-assembly
2020 / Microchemical Journal
In this work, L-cysteine-capped CdTe quantum dots (L-Cys/CdTe QDs) were used as novel chiral probes for in enantioselective recognition and… Continue reading Chiral recognition and quantitative analysis of tyrosine enantiomers using L-cysteine capped CdTe quantum dots: Circular dichroism, fluorescence, and theoretical calculation studies
2020 / International Journal of Biological Macromolecules
Cell interiors are extremely congested with biological macromolecules exerting crowding effect, influencing various physiognomies of protein life. Present work deals… Continue reading Consequence of macromolecular crowding on aggregation propensity and structural stability of haemoglobin under glycating conditions
2020 / Journal of Molecular Liquids
Mianserin hydrochloride (MIA), a drug, which belongs to a group of tetracyclic, noradrenergic and specific serotonergic antidepressants, is one of… Continue reading The impact of β-cyclodextrin on biological and chemical properties of mianserin hydrochloride in aqueous solution
2020 / Journal of Structural Biology
DciA is a newly discovered bacterial protein involved in loading the replicative helicase DnaB onto DNA at the initiation step… Continue reading Structural ensemble and biological activity of DciA intrinsically disordered region
2020 / European Biophysics Journal
The structural study of small heme-containing proteins, such as myoglobin, in the apo-form lacking heme has been extensively described, but… Continue reading Characterization of the apo-form of extracellular hemoglobin of Glossoscolex paulistus (HbGp) and its stability in the presence of urea
2020 / Phytochemistry Letters
A pair of new enantiomeric neoligans, (±)-neonardochinone A (1) were isolated from Nardostachys chinensis. The structure of 1 was determined by extensive spectroscopic… Continue reading (±)-Neonardochinone A, a pair of enantiomeric neoligans from Nardostachys chinensis with their anti-Alzheimer’s disease activities
