Leah Pandiscia, PhD
July 28, 2017
Whey proteins hydrolyzed by Bacillus licheniformis protease (BLP) form soft and turbid aggregate gels with potential food and biotechnological applications. The purpose… Continue reading Rheological and structural characterization of whey protein gelation induced by enzymatic hydrolysis
Leah Pandiscia, PhD
July 28, 2017
Exposure of PdAu24(2-PET)18 (2-PET: 2-phenylethylthiolate) to BINAS (1,1-binaphthyl-2,2-dithiol) leads to species of composition PdAu24(2-PET)18−2x(BINAS)x due to ligand exchange reactions. The BINAS adsorbs… Continue reading Isolation of atomically precise mixed ligand shell PdAu24 clusters
Leah Pandiscia, PhD
July 28, 2017
Transmembrane β-peptides are promising candidates for the design of well-controlled membrane anchors in lipid membranes. Here, we present the synthesis… Continue reading Heavy-Atom Labeled Transmembrane β-Peptides: Synthesis, CD-Spectroscopy and X-ray Diffraction Studies in Model Lipid Multi-layer
Leah Pandiscia, PhD
July 28, 2017
A novel terpenoid, named perovskiaol (1), was isolated from the cultured Perovskia atriplicifolia. Its structure was elucidated by comprehensive spectroscopic analysis… Continue reading A novel C22 terpenoid from the cultured Perovskia atriplicifolia
Leah Pandiscia, PhD
July 28, 2017
Gel formation by an N-fluorenyl-9-methoxycarbonyl (Fmoc)-based molecule was investigated and the chirality amplification observed during the self-assembly process could be… Continue reading Tuning of gel morphology with supramolecular chirality amplification by solvent strategy based on an Fmoc-amino acid building block
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Five 2-(2-phenylethyl)chromones including a new one, (5S,6R,7S,8R)-5,8-dichloro-6,7-dihydroxy-2-phenylethyl-5,6,7,8-tetrahydro-4H-chromen-4-one (1), and four known ones (2–5), were isolated from 150 mM NaCl-elicited Aquilaria sinensis cell… Continue reading Five 2-(2-Phenylethyl)chromones from Sodium Chloride-Elicited Aquilaria sinensis Cell Suspension Cultures
Leah Pandiscia, PhD
July 28, 2017
DNA damage in living cells is repaired by two main pathways, homologous recombination (HR) and non-homologous end joining (NHEJ). Of… Continue reading Biochemical characterization of plant Rad52 protein from rice (Oryza sativa)
Leah Pandiscia, PhD
July 28, 2017
Five michellamine-type dimeric naphthylisoquinoline alkaloids (NIQs), named michellamines A2, A3, A4, B2, and B3, have been isolated from the root… Continue reading HIV-inhibitory michellamine-type dimeric naphthylisoquinoline alkaloids from the Central African liana Ancistrocladus congolensis
Leah Pandiscia, PhD
July 28, 2017
A biphasic chiral recognition system based on chiral ligand exchange with Cu(II)-N-n-dodecyl-L-proline and hydroxypropyl-β-cyclodextrin as an additive was developed to… Continue reading Synergetic mechanism and enantioseparation of aromatic β-amino acids by biphasic chiral high-speed counter-current chromatography
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
We have previously shown that increasing the hydrophobicity of PEG by adding a methyl group to every other monomer unit… Continue reading Hydrophobicity-dependent effects of polymers on different protein conformations
Leah Pandiscia, PhD
July 28, 2017
Fib having intrinsically disordered αC domains is involved in coagulation cascade and thrombosis. Fib molecules forms prefibrillar oligomers at 30%,… Continue reading Aggregation of intrinsically disordered fibrinogen as the influence of backbone conformation
Leah Pandiscia, PhD
July 28, 2017
Human serum albumin (HSA) binding of anticancer plant alkaloid ellipticine has been studied in conjunction with assessing its association to… Continue reading Dimeric binding of plant alkaloid ellipticine to human serum proteins
Leah Pandiscia, PhD
July 28, 2017
Ablation of glucagon receptor signalling represents a potential treatment option for type 2 diabetes (T2DM). Additionally, activation of glucose-dependent insulinotropic… Continue reading Glucagon receptor antagonist and GIP agonist combination for diet induced obese mice
Leah Pandiscia, PhD
July 28, 2017
Six phenazines including three new ones were isolated from the culture of a marine actinomycete Streptomyces sp. 182SMLY. Based on the analyses… Continue reading New streptophenazines from marineStreptomyces sp. 182SMLY
Leah Pandiscia, PhD
July 28, 2017
Untreatable bacterial infections caused by a perpetual increase of antibiotic resistant strains represent a serious threat to human healthcare in… Continue reading VirB8-like protein TraH is crucial for DNA transfer in Enterococcus faecalis
Leah Pandiscia, PhD
July 28, 2017
In this work, the inhibitory effect of two isoflavonoids including daidzein and genistein on trypsin and their binding mechanism were… Continue reading Inhibitory effects of daidzein and genistein on trypsin: insights from spectroscopic and molecular docking studies
Leah Pandiscia, PhD
July 28, 2017
One of the major challenges in tissue engineering of small-diameter vascular grafts is to inhibit intimal hyperplasia and keep long-term… Continue reading Electrospun PELCL membranes loaded with QK peptide for enhancement of vascular endothelial cell growth
Leah Pandiscia, PhD
July 28, 2017