2016 / Journal of Integrative Medicine
To provide in vitro evidence of Psorinum treatment against cancer cells in a controlled study. Effects of homeopathic Psorinum 6× on cell… Continue reading Psorinum 6× triggers apoptosis signals in human lung cancer cells
2016 / Phytochemistry Letters
Four new aromatic butenolides named aspernolides H-K (1–4), along with three known compounds (5–7), were isolated from the metabolites of Aspergillus… Continue reading Antioxidant aromatic butenolides from an insect-associated Aspergillus iizukae
2016 / Tetrahedron
Four new bis-prenylated C6–C3 derivatives, illioliganpyranones B–C (1 and 4) and illioliganfuranones E–F (3 and 5), and six new mono-prenylated C6–C3 compounds, illioliganfuranone G (2), illioliganfuranol… Continue reading Antiviral mono- and bis-prenylated C6-C3 derivatives from the roots of Illicium oligandrum
2016 / Biochimica et Biophysica (BBA)- Proteins and Proteomics
α-Lactalbumin (aLA) has been shown to form complexes with oleic acid (OA), which may target cancer cells. We recently showed… Continue reading Liprotides made of α-lactalbumin and cis Fatty Acids form core-shell and multi-layer structures with a common membrane-targeting mechanism
2016 / Journal of Inorganic Biochemistry
The formation of quadruple-stranded DNA induced by planar metal complexes has particular interest in the development of novel anticancer drugs.… Continue reading Anthracene-Terpyridine Metal complexes as new G-Quadruplex DNA binders
2016 / Journal of Photochemistry and Photobiology B: Biology
To evaluate the biological preference of chiral drug candidates for molecular target DNA, the synthesis and characterization of a chiral… Continue reading Chiral copper(II) complex based on natural product rosin derivative as promising antitumour agent
2016 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
Although copper is essential to all living organisms, its potential toxicity to human health have aroused wide concerns. Previous studies… Continue reading Binding of copper to lysozyme: Spectroscopic, isothermal titration calorimetry and molecular docking studies
2016 / Biochimica et Biophysica Acta (BBA)- Biomembranes
Recently, several peptides have been studied regarding the defence process against pathogenic microorganisms, which are able to act against different… Continue reading Structural and functional evaluation of the palindromic alanine-rich antimicrobial peptide Pa-MAP2
2016 / Journal of Inorganic Biochemistry
Like chiral organic drugs, the chemical and biological properties of metal complexes can be dependent on chirality. Two pairs of… Continue reading Enantiomeric pair of copper(II) polypyridyl-alanine complexes: Effect of chirality on their interaction with biomolecules
2016 / Journal of Inorganic Biochemistry
Protein degradation leads to the formation of endogenous peptides, the biological activity of which is most often unknown. The peptide… Continue reading AGHLDDLPGALSAL: A hemoglobin fragment potentially competing with albumin to bind transition metal ions
2016 / Journal of Molecular Biology
APOBEC3F (A3F) is a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) family of proteins that can deaminate… Continue reading The in vitro Biochemical Characterization of an HIV-1 Restriction Factor A3F: Importance of loop 7 on both CD1 and CD2 for DNA binding and deamination
2016 / Phytochemistry
A seco-cucurbitane triterpene and two aristolane sesquiterpenes, named (24E)-3,4-seco-cucurbita-4,24-diene-3-hydroxy-26,29-dioic acid, (+)-1,2-didehydro-9-hydroxy-aristlone, and (+)-12-hydroxy-aristlone, were isolated from fruiting bodies of the… Continue reading Structures and biological activities of triterpenes and sesquiterpenes obtained from Russula lepida
2016 / Tetrahedron
Six new bromopyrrole alkaloids, longamides D–F (1–3), 3-oxethyl-4-[1-(4,5-dibromopyrrole-2-yl)-formamido]-butanoic acid methyl ester (4), 2-oxethyl-3-[1-(4,5-dibromopyrrole-2-yl)-formamido]-methyl propionate (5), and 9-oxethyl-mukanadin F (6), along… Continue reading Antifungal Bromopyrrole Alkaloids from the South China Sea Sponge Agelas sp
2016 / Journal of Cleaner Production
Synthetic dyes are commonly used for dyeing and printing in paper, textile and leather industries. However, some of these dyes… Continue reading Next generation greener leather dyeing process through recombinant green fluorescent protein
2016 / Tetrahedron: Asymmetry
Recent work by Wu et al. in connection with the first synthesis of the marine natural product plakinidone revealed that… Continue reading Reassignment of the absolute configuration of plakinidone from the sponge consortium Plakortis halichondrioides–Xestospongia deweerdtae using a combination of synthesis and a chiroptical approach
2016 / Journal of Nanomedicine and Nanotechnology
We have fabricated protein polymer-gold nanoparticle (P-GNP) nanocomposites that exhibit enhanced binding and delivery properties of the small hydrophobic molecule… Continue reading Engineered Protein Polymer-Gold Nanoparticle Hybrid Materials for Small Molecule Delivery
2016 / Phytochemistry Letters
Two new azaphilones, dechloroisochromophilone II (1) and epi-isochromophilone III (2), a new natural product, 5-hydroxy-4-methoxy-5,6-dihydro-2H-pyran-2-one (3), together with eleven known compounds, 4–14 were… Continue reading Bioactive azaphilones from the fungus Penicillium multicolor CM01
2016 / Journal of Biomolecular Structure and Dynamics
In our study, renal cancer is induced in rats making use of dimethylnitrosamine (DMN). G1 – Group 1 were control… Continue reading Structural transition of kidney cystatin in dimethylnitrosamine-induced renal cancer in rats: identification as a novel biomarker for kidney cancer and prognosis
2016 / Helvetica Chimica Acta
A simple, one-step, stereoconservative synthesis of diamine-based peptidomimetics is described, by split-Ugi multicomponent reaction, involving chiral N-protected amino acids and α-substituted isocyanoacetate.… Continue reading Split-Ugi Reaction with Chiral Compounds: Synthesis of Piperazine- and Bispidine-Based Peptidomimetics
2016 / Ferroelectrics
We have synthesized a racemic and enantiomerically enriched all-organic paramagnetic nitroxide radical (NR) liquid crystalline (LC) compound, which contains a… Continue reading Paramagnetic nitroxide radical liquid crystalline compounds with methyl di(ethylene glycol) chain
