2019 / Langmuir
Protein-encapsulated nanoclusters (NCs) are emerging as a versatile platform for in-vivo imaging and other biomedical applications due to their ultrasmall… Continue reading Adsorption and Conformation of Bovine Serum Albumin with Blue-Emitting Gold Nanoclusters at the Air/Water and Lipid/Water Interfaces
2019 / Langmuir
π-Conjugated porphyrins have aroused particular attention for nanofabrication and biomimics; however, little attention has been paid to porphyrins-based chiral analysis… Continue reading Chiral Enantioselective Assemblies Induced from Achiral Porphyrin by l- and d-Lysine
2019 / Chemical Research in Toxicology
Human phospholipid scramblases are a family of four homologous transmembrane proteins (hPLSCR1–4) mediating phospholipids (PLs) translocation in plasma membrane upon… Continue reading Heavy-Metals-Mediated Phospholipids Scrambling by Human Phospholipid Scramblase 3: A Probable Role in Mitochondrial Apoptosis
2019 / JACS
Peptides with pharmaceutical activities are attractive drug leads, and knowledge of their mode-of-action is essential for translation into the clinic.… Continue reading Is the Mirror Image a True Reflection? Intrinsic Membrane Chirality Modulates Peptide Binding
2019 / Crystals
Protein phase separation and protein liquid cluster formation have been observed and analysed in protein crystallization experiments and, in recent… Continue reading Multi-Step Concanavalin A Phase Separation and Early-Stage Nucleation Monitored Via Dynamic and Depolarized Light Scattering
2019 / ACS Nano
To mimic native insulin activity, materials have been developed that encapsulate insulin, glucose oxidase, and catalase for glucose-responsive insulin delivery.… Continue reading Glucose-Responsive Nanoparticles for Rapid and Extended Self-Regulated Insulin Delivery
2019 / Bioorganic Chemistry
The antiglycation effects of three structurally different phytosterols (PS) including stigmasterol, β-sitosterol, and γ-oryzanol on bovine serum albumin (BSA) were… Continue reading The noncovalent conjugations of bovine serum albumin with three structurally different phytosterols exerted antiglycation effects: A study with AGEs-inhibition, multispectral, and docking investigations
2019 / RSC Advances
We described a novel synthetic peptide in which a glutamine residue binds through hydrogen bonding to a guanine-base and a… Continue reading Selective recognition of human telomeric G-quadruplex with designed peptide via hydrogen bonding followed by base stacking interactions
2019 / Journal of Organic Chemistry
Genome sequencing and bioinformatic analysis have identified numerous cryptic gene clusters that have the potential to produce novel natural products.… Continue reading Discovery of the Streptoketides by Direct Cloning and Rapid Heterologous Expression of a Cryptic PKS II Gene Cluster from Streptomyces sp. Tü 6314
2019 / Foods
Oral allergy syndrome (OAS) describes an allergic reaction where an individual sensitized by pollen allergens develops symptoms after eating certain… Continue reading Purification and Characterization of Pathogenesis Related Class 10 Panallergens
2019 / International Journal of Biological Macromolecules
The misfolding, aggregation and fibrillation of human islet amyloid polypeptide (hIAPP) has been acknowledged as a hallmark event in type-II… Continue reading Cichoric acid from witloof inhibit misfolding aggregation and fibrillation of hIAPP
2019 / Food & Function
Alzheimer’s disease (AD) is a neurodegenerative disease. The molecular mechanisms of AD are not yet clear, and no effective treatments… Continue reading Xanthohumol inhibits tau protein aggregation and protects cells against tau aggregates
2019 / Journal of Physical Chemistry B
Nucleic acids (DNA) and neurotransmitters integrate together in the brain of organisms to make powerful information processing systems. Dopamine is… Continue reading Multimodal Interactions of Dopamine Hydrochloride with the Groove Region of DNA: A Key Factor in the Enhanced Stability of DNA
2020 / Journal of Medical Genetics
POLG2 associated disorders belong to the group of mitochondrial DNA (mtDNA) diseases and present with a heterogeneous clinical spectrum, various age… Continue reading Whole exome sequencing identifies a homozygous POLG2 missense variant in an adult patient presenting with optic atrophy, movement disorders, premature ovarian failure and mitochondrial DNA depletion
2020 / International Journal of Biological Macromolecules
Point mutations in gene sequence often lead to protein misfolding or destabilization which is a well-known cause of a number… Continue reading Effect of disease-linked mutations on the structure, function, stability and aggregation of human carbonic anhydrase II
2020 / Phytochemistry
Nine undescribed triterpenoids (jughopenoids A-I), including seven nortriterpenoids and two normal triterpenoids, together with fourteen known analogues, were isolated from… Continue reading Triterpenoids from the barks of Juglans hopeiensis
2019 / RSC Advances
The introduction of chirality in an achiral system will not only help avoid the tedious and expensive synthesis of chiral… Continue reading Different phase-dominated chiral assembly of polyfluorenes induced by chiral solvation: axial and supramolecular chirality
2019 / Pharmaceutics
The aim of this study was to investigate the effects of various stabilizers on the encapsulation efficiency and release of… Continue reading Effect of Stabilizers on Encapsulation Efficiency and Release Behavior of Exenatide-Loaded PLGA Microsphere Prepared by the W/O/W Solvent Evaporation Method
2019 / Journal of Structural Biology
DivIVA or Wag31, which is an essential pole organizing protein in mycobacteria, can self-assemble at the negatively curved side of… Continue reading Higher order assembling of the mycobacterial polar growth factor DivIVA/Wag31
2019 / International Journal of Biological Macromolecules
This study is based on the analysis of the recent trend of medication in neurodegenerative diseases. Due to the asymptomatic… Continue reading An insight into the inhibition of fibrillation process verses disaggregation of preformed fibrils of bovine serum albumin by isoprenaline hydrochloride
