Leah Pandiscia, PhD
October 11, 2018
Chlamydomonas reinhardtii is a single celled alga that undergoes apoptosis in response to UV-C irradiation. UVI31+, a novel UV-inducible DNA endonuclease… Continue reading Structural characterization of a novel KH-domain containing plant chloroplast endonuclease
Leah Pandiscia, PhD
October 11, 2018
Helical polyaniline nanofibers having a molar ellipticity as high as 5.8 × 105 deg cm2dmol−1 are produced via a self-assembly process of the amine-capped… Continue reading Supramolecular chirality control viaself-assembly of oligoaniline in the chemical oxidative polymerization process
Leah Pandiscia, PhD
October 11, 2018
c-MYC proto-oncogene harbours a transcriptioninhibitory quadruplex-forming scaffold (Pu27) upstream P1 promoter providing anti-neoplastic therapeutic target. Previous reports showed the binding… Continue reading Site-specific amino acid substitution in dodecameric peptides determines the stability and unfolding of c-MYC quadruplex promoting apoptosis in cancer cells
Leah Pandiscia, PhD
October 11, 2018
Type III antifreeze proteins (AFP III) have been widely recognized as one class of ice-binding proteins produced by several biological… Continue reading Ice-binding site of surface-bound type III antifreeze protein partially decoupled from water
Leah Pandiscia, PhD
October 11, 2018
The wide range of applications of copper have caused widespread concern about its toxicity. However, few studies have reported the… Continue reading Exploring the binding interaction between copper ions and Candida rugosa lipase
Leah Pandiscia, PhD
October 11, 2018
Five novel and rare cadinane-type sesquiterpene glycosides, cornucadinoside A-E (1–5) were isolated from water extract of the fruit of Cornus officinalis Sieb.… Continue reading Unusual cadinane-type sesquiterpene glycosides with α-glucosidase inhibitory activities from the fruit of Cornus officinalis Sieb. et Zuuc.
Leah Pandiscia, PhD
October 11, 2018
Lipoxygenase (LOX) from Anabaena sp. PCC 7120 (Ana-rLOX) offers important applications in the food industry, especially for improving aroma and… Continue reading Consensus design for improved thermostability of lipoxygenase from Anabaena sp. PCC 7120
Leah Pandiscia, PhD
October 11, 2018
Nine new neolignan glycosides (1–9), viburfordosides A–I, two new neolignans, fordianes A and B (10, 11), and seven known analogues (12–18)… Continue reading Neolignan Constituents with Potential Beneficial Effects in Prevention of Type 2 Diabetes from Viburnum fordiae Hance Fruits
Leah Pandiscia, PhD
October 11, 2018
Seven (half‐)titanocene alkoxide complexes, [Cp2TiCl(OEt)], [Cp2TiCl(O‐2‐Bu)], [Cp2TiCl(OCH2CF2CF2H)], [CpTiCl2(OEt)], [CpTiCl2(O‐(S)‐2‐Bu)], [CpTiCl2(OCH2CF3)], and [Cp2TiCl(OCH2CF3)], were synthesized and employed in lactide coordination polymerization.… Continue reading Employing (half‐)titanocene complexes as initiators for the synthesis of end‐functionalized polylactides by coordination polymerization
Leah Pandiscia, PhD
October 11, 2018
The biosynthesis of heme is strictly regulated, probably because of the toxic effects of excess heme and its biosynthetic precursors.… Continue reading Heme-dependent Inactivation of 5-Aminolevulinate Synthase from Caulobacter crescentus
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
Fly ash particles can contribute to haze and adverse health outcomes. In this study, two mucins, one from bovine submaxillary… Continue reading Interactions of Fly Ash Particles with Mucin and Serum Albumin
Leah Pandiscia, PhD
October 11, 2018
This work reports the toxicity of small silver nanoparticles (nanoAg, 20 nm) and silver ions (Ag+) to the red blood cells… Continue reading In vitro assessment of the toxicity of small silver nanoparticles and silver ions to the red blood cells
Leah Pandiscia, PhD
October 11, 2018
The use of antibacterial agents, triclosan (TCS) and triclocarban (TCC), in personal care products can result in direct human exposure.… Continue reading Binding of triclosan and triclocarban to pepsin: DFT, spectroscopic and dynamic simulation studies
Leah Pandiscia, PhD
October 11, 2018
The ability to recognize the molecular chirality of enantiomers is extremely important owing to their critical role in drug development… Continue reading Nanoparticle-based Chemiluminescence for Chiral Discrimination of Thiol-Containing Amino Acids
Leah Pandiscia, PhD
October 11, 2018
The asymmetric induction leading to a one‐handed helix was investigated in the anionic and radical copolymerization of triphenylmethyl methacrylate (TrMA)… Continue reading Helix‐sense‐selective copolymerization of triphenylmethyl methacrylate with chiral 2‐isopropenyl‐4‐phenyl‐2‐oxazoline
Leah Pandiscia, PhD
October 11, 2018
A novel red color–related pigment–binding protein, named LvPBP75, isolated from the shell of Litopenaeus vannamei has recently been identified as… Continue reading Functional and structural properties of red color–related pigment–binding protein from the shell of Litopenaeus vannamei
Leah Pandiscia, PhD
October 11, 2018
Despite their importance for antibody architecture and design, the principles governing antibody domain stability are still not understood in sufficient… Continue reading A single residue switch reveals principles of antibody domain integrity
Leah Pandiscia, PhD
October 11, 2018
By treating with histone-deacetylase inhibitor valproate sodium, three new heterdimeric tetrahydroxanthone–chromanone lactones chrysoxanthones A–C (1–3), along with 17 known compounds… Continue reading Chrysoxanthones A–C, Three New Xanthone–Chromanone Heterdimers from Sponge-Associated Penicillium chrysogenum HLS111 Treated with Histone Deacetylase Inhibitor
Leah Pandiscia, PhD
October 11, 2018