Found 9617 Results / Page 452 of 481

Alkali base triggered intramolecular charge transfer metallogels based on symmetrical A–π–D-chiral-D–π–A type ligands

2016 / Soft Matter

Three L-tartaric acid based symmetrical A–π–D-chiral-D–π–A type structural isomeric nitrobenzylidenes (1–3) have been synthesized with intent to achieve isomer specific metallogels… Continue reading Alkali base triggered intramolecular charge transfer metallogels based on symmetrical A–π–D-chiral-D–π–A type ligands

Leah Pandiscia, PhD

Enhancement of oral insulin bioavailability:In vitro and in vivo assessment of nanoporous stimuli-responsive hydrogel microparticles

2016 / Expert Opinion on Drug Delivery

Oral insulin administration suffers gastrointestinal tract (GIT) degradation and inadequate absorption from the intestinal epithelium resulting in poor bioavailability. This… Continue reading Enhancement of oral insulin bioavailability:In vitro and in vivo assessment of nanoporous stimuli-responsive hydrogel microparticles

Leah Pandiscia, PhD

Structural characterization of the C-terminal coiled coil domains of wild-type and kidney disease associated mutants of Apolipoprotein L1

2016 / The FEBS Journal

Trypanosomes that cause sleeping sickness endocytose apolipoprotein L1 (APOL1)-containing trypanolytic factors from human serum, leading to trypanolytic death through generation… Continue reading Structural characterization of the C-terminal coiled coil domains of wild-type and kidney disease associated mutants of Apolipoprotein L1

Leah Pandiscia, PhD

Novel insights into renal d-amino acid oxidase accumulation: propiverine changes DAAO localization and peroxisomal size in vivo

2016 / Archives of Toxicology

Chronic exposure to propiverine, a frequently prescribed pharmaceutical for treatment of overactive bladder and incontinence, provokes massive protein accumulation in… Continue reading Novel insights into renal d-amino acid oxidase accumulation: propiverine changes DAAO localization and peroxisomal size in vivo

Leah Pandiscia, PhD

The role of the C-terminal region on the oligomeric state and enzymatic activity of Trypanosoma cruzi hypoxanthine phosphoribosyl transferase

2016 / Biochimica et Biophysica Acta-Proteins and Proteomics

Hypoxanthine phosphoribosyl transferase from Trypanosoma cruzi (TcHPRT) is a critical enzyme for the survival of the parasite. This work demonstrates that the… Continue reading The role of the C-terminal region on the oligomeric state and enzymatic activity of Trypanosoma cruzi hypoxanthine phosphoribosyl transferase

Leah Pandiscia, PhD

Measuring the bioactivity and molecular conformation of typically globular proteins with phenothiazine-derived methylene blue in solid and in solution: A comparative study using photochemistry and computational chemistry

2016 / Journal of Photochemistry and Photobiology B: Biology

Methylene blue is a phenothiazine agent, that possesses a diversity of biomedical and biological therapeutic purpose, and it has also… Continue reading Measuring the bioactivity and molecular conformation of typically globular proteins with phenothiazine-derived methylene blue in solid and in solution: A comparative study using photochemistry and computational chemistry

Leah Pandiscia, PhD
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