Found 9617 Results / Page 87 of 481

A Lynch syndrome-associated mutation at a Bergerat ATP-binding fold destabilizes the structure of the DNA mismatch repair endonuclease MutL

2020 / Journal of Biological Chemistry

In humans, mutations in genes encoding homologs of the DNA mismatch repair endonuclease MutL cause a hereditary cancer that is… Continue reading A Lynch syndrome-associated mutation at a Bergerat ATP-binding fold destabilizes the structure of the DNA mismatch repair endonuclease MutL

Leah Pandiscia, PhD

Synthesis and evaluation of Na+/K+-ATP-ase inhibiting and cytotoxic in vitro activities of oleandrigenin and its selected 17β-(butenolidyl)- and 17β-(3-furyl)- analogues

2020 / European Journal of Medicinal Chemistry

Natural cardiac-active principles built upon the 14,16β-dihydroxy-5β,14β-androstane core and bearing a heterocyclic substituent at 17β, in particular, a cardenolide –… Continue reading Synthesis and evaluation of Na+/K+-ATP-ase inhibiting and cytotoxic in vitro activities of oleandrigenin and its selected 17β-(butenolidyl)- and 17β-(3-furyl)- analogues

Leah Pandiscia, PhD

Catalytic properties and crystal structure of UDP-galactose 4-epimerase-like l-threonine 3-dehydrogenase from Phytophthora infestans

2020 / Enzyme and Microbial Technology

We report, for the first time, the three-dimensional structure and biochemical properties of a UDP-galactose 4-epimerase-like l-threonine 3-dehydrogenase (GalE-like L-ThrDH) from Phytophthora… Continue reading Catalytic properties and crystal structure of UDP-galactose 4-epimerase-like l-threonine 3-dehydrogenase from Phytophthora infestans

Leah Pandiscia, PhD

Smart phone assisted, rapid, simplistic, straightforward and sensitive biosensing of cysteine over other essential amino acids by β-cyclodextrin functionalized gold nanoparticles as a colorimetric probe

2020 / New Journal of Chemistry

In this paper, a β-cyclodextrin (β-CD) functionalized gold nanoparticle (β-CD AuNP) based simple, rapid, on-site and naked eye colorimetric sensor… Continue reading Smart phone assisted, rapid, simplistic, straightforward and sensitive biosensing of cysteine over other essential amino acids by β-cyclodextrin functionalized gold nanoparticles as a colorimetric probe

Leah Pandiscia, PhD

Synthesis and characterization of host-guest inclusion complex of β-cyclodextrin with 4,4′-methylenedianiline by diverse methodologies

2020 / Journal of Molecular Liquids

In the present article the host-guest inclusion of 4,4′-Methylenedianiline (MDA) (guest) into β-Cyclodextrin (β-CD) (Host) hydrophobic cavity was done and… Continue reading Synthesis and characterization of host-guest inclusion complex of β-cyclodextrin with 4,4′-methylenedianiline by diverse methodologies

Leah Pandiscia, PhD

The chemical constituents of Gentiana macrophylla pall. under acidic condition using gentiopicroside-rich secoiridoids extract

2020 / Phytochemistry Letters

The chemical constituents of Gentiana macrophylla Pall. under acidic condition were explored using gentiopicroside-rich secoiridoids extract treated with hydrochloric acid. 2 new… Continue reading The chemical constituents of Gentiana macrophylla pall. under acidic condition using gentiopicroside-rich secoiridoids extract

Leah Pandiscia, PhD

In vivo and in vitro studies on inactivation of selenium containing protein- glutathione peroxidase 3 in mice nephrocytes caused by lead

2020 / Ecotoxicology and Environmental Safety

Glutathione peroxidases (Gpxs) play vital roles in elimination of hydroperoxide and other reactive oxygen species through catalyzing reduced glutathione to… Continue reading In vivo and in vitro studies on inactivation of selenium containing protein- glutathione peroxidase 3 in mice nephrocytes caused by lead

Leah Pandiscia, PhD

An efficient approach for rapid detection of polymyxins B based on the optically active supramolecular aggregates of water-soluble perylene diimide

2020 / Sensors and Actuators B: Chemical

Antibiotic residue in food products has aroused considerable public concerns all over the world. It is of great significance to… Continue reading An efficient approach for rapid detection of polymyxins B based on the optically active supramolecular aggregates of water-soluble perylene diimide

Leah Pandiscia, PhD

Development of Injectable Thermosensitive Polypeptide Hydrogel as Facile Radioisotope and Radiosensitizer Hotspot for Synergistic Brachytherapy

2020 / Acta Biomaterialia

Brachytherapy is considered to be an unparalleled form of conformal radiation therapy, which involves the delivery of radiation directly to… Continue reading Development of Injectable Thermosensitive Polypeptide Hydrogel as Facile Radioisotope and Radiosensitizer Hotspot for Synergistic Brachytherapy

Leah Pandiscia, PhD

Physicochemical and emulsifying properties of mussel water-soluble proteins as affected by lecithin concentration

2020 / International Journal of Biological Macromolecules

The effects of lecithin addition at different concentrations (0–2.0%) on the physicochemical and emulsifying properties of mussel water-soluble proteins (MWP)… Continue reading Physicochemical and emulsifying properties of mussel water-soluble proteins as affected by lecithin concentration

Leah Pandiscia, PhD

Reduction of a disulfide-constrained oligo-glutamate peptide triggers self-assembly of β2-type amyloid fibrils with the chiroptical properties determined by supramolecular chirality

2020 / International Journal of Biological Macromolecules

Disulfide bonds prevent aggregation of globular proteins by stabilizing the native state. However, a disulfide bond within a disordered state… Continue reading Reduction of a disulfide-constrained oligo-glutamate peptide triggers self-assembly of β2-type amyloid fibrils with the chiroptical properties determined by supramolecular chirality

Leah Pandiscia, PhD
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