The coordination of zinc ions by histidine residues of amyloid-beta peptide (Aβ) plays a critical role in the zinc-induced Aβ… Continue reading The English (H6R) Mutation of the Alzheimer’s Disease Amyloid-β Peptide Modulates Its Zinc-Induced Aggregation
Leah Pandiscia, PhD
July 30, 2020
Nanoscale protein materials are highly convenient as vehicles for targeted drug delivery because of their structural and functional versatility. Selective… Continue reading Engineering Protein Nanoparticles Out from Components of the Human Microbiome
Leah Pandiscia, PhD
July 30, 2020
The allosteric O2 release of haemoglobin (Hb) allows for efficient O2 delivery from the lungs to the tissues. However, allostery is weakened… Continue reading Haemoglobin(βK120C)–albumin trimer as an artificial O2 carrier with sufficient haemoglobin allostery
Leah Pandiscia, PhD
July 30, 2020
The diversity of DNA duplex structures is limited by a binary pair of hydrogen-bonded motifs. Here we show that poly(thymine)… Continue reading A poly(thymine)–melamine duplex for the assembly of DNA nanomaterials
Leah Pandiscia, PhD
July 30, 2020
Fluorescent, pH dependent and water soluble copper nanoclusters (CuNCs) were synthesized using lysozyme (lyz) as the stabilizing agent to give… Continue reading Lysozyme coated copper nanoclusters for green fluorescence and their utility in cell imaging
Leah Pandiscia, PhD
July 30, 2020
In this work, a kind of chiral helical polymer PDTDH of 9,9-dipropynylfluorene skeleton structure were prepared. The structure and chiral… Continue reading Chiral PDTDH-based electrode modification material for L/D-tartaric acid electrochemical sensing
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
Elastin-like polypeptides (ELP) have been widely used in the biomaterials community due to their controllable, thermoresponsive properties and biocompatibility. Motivated… Continue reading Placement of tyrosine residues as a design element for tuning the phase transition of elastin-peptide-containing conjugates: experiments and simulations
Leah Pandiscia, PhD
July 30, 2020
A simple approach to synthesize new highly substituted 4H-pyran derivatives is described. Efficient Et3N acts as a readily accessible catalyst… Continue reading Ultrasound-assisted multicomponent synthesis of 4H-pyrans in water and DNA binding studies
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
Copper-doped TiO2 was prepared with a sol–gel chemical method. Various concentrations (3, 6, and 9 wt%) of Cu dopant were employed.… Continue reading Dye degradation performance, bactericidal behavior and molecular docking analysis of Cu-doped TiO2 nanoparticles
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
We investigated the structural and luminescent properties of Eu3+-doped CaHfO3, which was synthesized using the solid-state reaction method. The crystal… Continue reading Structural and luminescent properties of Eu-ion-doped CaHfO3
Leah Pandiscia, PhD
July 30, 2020
Rab proteins, a family of small guanosine triphosphatases, play key roles in intracellular membrane trafficking and the regulation of various… Continue reading The dynamic structure of Rab35 is stabilized in the presence of GTP under physiological conditions
Leah Pandiscia, PhD
July 30, 2020
Although the mystery molecule p53 has been studied extensively, still several unknown mechanisms need to be elucidated. Being a central… Continue reading Conformational dynamics of p53 N-terminal TAD2 region under different solvent conditions
Leah Pandiscia, PhD
July 30, 2020
Anti-pseudorabies virus (PRV) activity-guided isolation of an endophytic fungus Talaromyces purpureogenus resulted in seven rare polycyclic meroterpenoids talaromyolides E–K, together… Continue reading Polycyclic meroterpenoids, talaromyolides E − K for antiviral activity against pseudorabies virus from the endophytic fungus Talaromyces purpureogenus
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
Molecules self-assembly in confined space such as in cell to form microfilaments is a crucial process to achieve special functionality.… Continue reading Thermolysin-triggered short peptides self-assembly in confined space and application in cell culturing
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020
Leah Pandiscia, PhD
July 30, 2020