2021 / Enzyme and microbial technology
The ene reductases (ERs) from the old yellow enzymes (OYEs) family have the ability to reduce activated alkenes to generate… Continue reading Identification of four ene reductases and their preliminary exploration in the asymmetric synthesis of (R)-dihydrocarvone and (R)-profen derivatives
2021 / nanomaterials
A chiral molecular gelation system, as a chiral host, was used to effectively realize enantioselectivity using the simple carboxylic acid… Continue reading Enantioselective Self-Assembled Nanofibrillar Network with Glutamide-Based Organogelator
2021 / Nature Communications
Manmade high-performance polymers are typically non-biodegradable and derived from petroleum feedstock through energy intensive processes involving toxic solvents and byproducts.… Continue reading Microbial production of megadalton titin yields fibers with advantageous mechanical properties
2021 / Nature Communications
Skeletal muscle has a remarkable ability to regenerate owing to its resident stem cells (also called satellite cells, SCs). SCs… Continue reading Translational control by DHX36 binding to 5′UTR G-quadruplex is essential for muscle stem-cell regenerative functions
2021 / Nature Communications
Development of a versatile, sustainable and efficient photosynthesis system that integrates intricate catalytic networks and energy modules at the same… Continue reading A host–guest semibiological photosynthesis system coupling artificial and natural enzymes for solar alcohol splitting
2021 / Scientific Reports
Bioinspired fluorescence, being widely explored for imaging purposes, faces challenges in delivering bright biocompatible sources. While quite a few techniques… Continue reading Amplified spontaneous emission and gain in highly concentrated Rhodamine-doped peptide derivative
2021 / Journal of Biomolecular Structure and Dynamics
Biochemical activities of Fluorescein, Rose Bengal and Rhodamine 101 were studied by DNA binding, antibacterial and cytotoxic studies. DNA binding… Continue reading A comparison on the biochemical activities of Fluorescein disodium, Rose Bengal and Rhodamine 101 in the light of DNA binding, antimicrobial and cytotoxic study
2021 / Fitoterpia
Four new alkaloids, nonialkaloids A–D (1–4) and six known analogues (5–10) were isolated from the noni juice. Among the new… Continue reading New alkaloids from the noni juice with potential α-glucosidase inhibitory activity
2021 / Bioorganic Chemistry
Neuroinflammation is emerging as a crucial reason of major neurodegenerative diseases in recent years. Increasingly evidences have supported that bioactive… Continue reading Neuroprotective and anti-inflammatory phenylethanoid glycosides from the fruits of Forsythia suspensa
2021 / Archives of Pharmacal Research
Ginkgo biloba (Ginkgoaceae), commonly known as “ginkgo”, is called a living fossil, and it has been cultivated early in human… Continue reading Ginkwanghols A and B, osteogenic coumaric acid-aliphatic alcohol hybrids from the leaves of Ginkgo biloba
2021 / Fitoterpia
A methanolic extract of Thai Piper ribesoides showed preferential cytotoxicity against PANC-1 human pancreatic cancer cells under a nutrient-deprived condition,… Continue reading Chemical constituents of Thai Piper ribesoides and their antiausterity activities against the PANC-1 human pancreatic cancer cell line
2021 / Bioorganic Chemistry
Thirty new pentacyclic triterpenoids, including five oleanane-type (1–5), twenty-three ursane-type (9–23, 26–33) and two taraxerane-type (24 and 25), along with… Continue reading Oxygenated pentacyclic triterpenoids from the stems and branches of Enkianthus chinensis
2021 / Nature Communications
Budding yeast Dpb4 (POLE3/CHRAC17 in mammals) is a highly conserved histone fold protein that is shared by two protein complexes:… Continue reading Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes
2021 / Scientific reports
Oncostatin M (OSM) is a pleiotropic, interleukin-6 family inflammatory cytokine that plays an important role in inflammatory diseases, including inflammatory… Continue reading Bioactive recombinant human oncostatin M for NMR-based screening in drug discovery
2021 / Communication Biology
Major facilitator superfamily_2 transporters are widely found from bacteria to mammals. The melibiose transporter MelB, which catalyzes melibiose symport with… Continue reading X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB
2021 / Scientific reports
CXXC5 is a member of the zinc-finger CXXC family that binds to unmethylated CpG dinucleotides. CXXC5 modulates gene expressions resulting… Continue reading A CpG island promoter drives the CXXC5 gene expression
2021 / Scientific reports
Human acidic fibroblast growth factor (hFGF1) is an all beta-sheet protein that is involved in the regulation of key cellular… Continue reading Characterization of the structural forces governing the reversibility of the thermal unfolding of the human acidic fibroblast growth factor
2021 / Scientific reports
Hepatocellular carcinoma (HCC) still presents poor prognosis with high mortality rate, despite of the improvement in the management. The challenge… Continue reading Potent antitumor activity of a glutamyltransferase-derived peptide via an activation of oncosis pathway
2021 / Scientific reports
Proteinase-activated receptor-1 (PAR1), triggered by thrombin and other serine proteinases such as tissue kallikrein-4 (KLK4), is a key driver of… Continue reading A KLK4 proteinase substrate capture approach to antagonize PAR1
2021 / Communication Chemistry
Controlled formation of desired lanthanide supramolecular complexes is challenging because of the difficulties in predicting coordination geometry, as well as… Continue reading Helicate-to-tetrahedron transformation of chiral lanthanide supramolecular complexes induced by ionic radii effect and linker length
