Interfacial Organization of Achiral Porphyrins via a Unidirectional Compression: a General Method for Chiroptical Porphyrin Assemblies of Selected Chirality

2016 / Physical Chemistry Chemical Physics

Porphyrins are considered to be important scaffolds bridging supramolecular chemistry and chiral chemistry, where chirality selection via physical effects such as directional… Continue reading Interfacial Organization of Achiral Porphyrins via a Unidirectional Compression: a General Method for Chiroptical Porphyrin Assemblies of Selected Chirality

Leah Pandiscia, PhD

Photoactive g-C3N4 Nanosheets for Light-Induced Suppression of Alzheimer’s β-Amyloid Aggregation and Toxicity

2016 / Advanced Healthcare Materials

Graphitic carbon nitride (g-C3N4) has a suppressive capability toward Alzheimer’s Aβ aggregation under light-illumination. Photoinduced electrons of g-C3N4 generate reactive oxygen resulting… Continue reading Photoactive g-C3N4 Nanosheets for Light-Induced Suppression of Alzheimer’s β-Amyloid Aggregation and Toxicity

Leah Pandiscia, PhD

Enantio- and diastereoselective polymerization: asymmetric allylic alkylation catalyzed by a planar-chiral Cp′Ru complex

2016 / Polymer Chemistry

In this study, we examined the regio-, diastereo-, and enantioselective polymerization using asymmetric allylic alkylation catalyzed by a planar-chiral cyclopentadienyl-ruthenium… Continue reading Enantio- and diastereoselective polymerization: asymmetric allylic alkylation catalyzed by a planar-chiral Cp′Ru complex

Leah Pandiscia, PhD

N-acetyl-l-methionine is a superior protectant of human serum albumin against post-translational oxidation as compared to N-acetyl-l-tryptophan

2016 / Biochemistry and Biophysics Reports

Sodium octanoate and N-acetyl-L-tryptophan (N-AcTrp) are widely used as stabilizers during pasteurization and storage of albumin products. However, as compared… Continue reading N-acetyl-l-methionine is a superior protectant of human serum albumin against post-translational oxidation as compared to N-acetyl-l-tryptophan

Leah Pandiscia, PhD

Tick receptor for outer surface protein A from Ixodes ricinus — the first intrinsically disordered protein involved in vector-microbe recognition

2016 / Scientific Reports

The tick receptor for outer surface protein A (TROSPA) is the only identified factor involved in tick gut colonization by… Continue reading Tick receptor for outer surface protein A from Ixodes ricinus — the first intrinsically disordered protein involved in vector-microbe recognition

Leah Pandiscia, PhD

Anticancer activity of heterodinuclear ruthenium(II)–platinum(II) complexes as photochemotherapeutic agents

2016 / Inorganica Chimica Acta

The purpose of the present study was to investigate the DNA-binding properties of mononuclear ruthenium(II) complex [Ru(tBu2bpy)2(dpp)]2+ and heterodinuclear ruthenium(II)–platinum(II) complexes… Continue reading Anticancer activity of heterodinuclear ruthenium(II)–platinum(II) complexes as photochemotherapeutic agents

Leah Pandiscia, PhD

2’-O-Methyl- and 2’-O-propargyl-5-methylisocytidine: synthesis, properties and impact on the isoCd – dG and the isoCd – isoGd base pairing in nucleic acids with parallel and antiparallel strand orientation

2016 / Organic and Biomolecular Chemistry

Oligonucleotides containing 2′-O-methylated 5-methylisocytidine (3) and 2′-O-propargyl-5-methylisocytidine (4) as well as the non-functionalized 5-methyl-2′-deoxyisocytidine (1b) were synthesized. MALDI-TOF mass spectra… Continue reading 2’-O-Methyl- and 2’-O-propargyl-5-methylisocytidine: synthesis, properties and impact on the isoCd – dG and the isoCd – isoGd base pairing in nucleic acids with parallel and antiparallel strand orientation

Leah Pandiscia, PhD

Daboxin P, a Major Phospholipase A2 Enzyme from the IndianDaboia russelii russelii Venom Targets Factor X and Factor Xa for Its Anticoagulant Activity

2016 / PLoS ONE

In the present study a major protein has been purified from the venom of Indian Daboia russelii russelii using gel filtration, ion… Continue reading Daboxin P, a Major Phospholipase A2 Enzyme from the IndianDaboia russelii russelii Venom Targets Factor X and Factor Xa for Its Anticoagulant Activity

Leah Pandiscia, PhD