2016 / Chinese Chemical Letters
In searching for more bioactive compounds, phytochemical investigations on the acetone extract of the leaves of Nicotiana tabacum resulted in the isolation… Continue reading Sesquiterpenes from the leaves of Nicotiana tabacum and their anti-tobacco mosaic virus activity
2016 / Journal of Biomolecular Structure and Dynamics
Calcium/calmodulin-dependent protein kinase IV (CaMKIV) is a multifunctional enzyme which belongs to the Ser/Thr kinase family. CaMKIV plays important role… Continue reading Urea-induced denaturation of human calcium/calmodulin-dependent protein kinase IV: a combined spectroscopic and MD simulation studies
2016 / Vaccine
Diphtheria toxin mutant CRM197 is a common carrier protein for glycoconjugate vaccines, which has been proven an effective protein vector for,… Continue reading Evaluation of the non-toxic mutant of the diphtheria toxin K51E/E148K as carrier protein for meningococcal vaccines
2016 / JACS
Quadruplex (G4) nucleic acids, a family of secondary structures formed by guanine-rich sequences, exhibit an important structural polymorphism. We demonstrate… Continue reading Quadruplex Turncoats: Cation-Dependent Folding and Stability of Quadruplex-DNA Double Switches
2016 / Analytical Chemistry
In this present work, we proposed a colorimetric strategy for simultaneous detection of histidine and cysteine based on G-quadruplex-Cu(II) metalloenzyme… Continue reading Colorimetric Strategy for Highly Sensitive and Selective Simultaneous Detection of Histidine and Cysteine Based on G-Quadruplex-Cu(II) Metalloenzyme
2016 / Journal of Biomedical Materials Research Part A
Growth factor delivered in combination with animal-derived collagen materials has been used to accelerate bone fracture healing in human patients.… Continue reading Acceleration of bone formation during fracture healing by poly(pro–hyp–gly)10 and basic fibroblast growth factor containing polycystic kidney disease and collagen-binding domains from Clostridium histolyticum collagenase
2016 / Nucleic Acids Research
Kaposi’s sarcoma associated herpesvirus (KSHV) establishes life-long latent infection by persisting as an extra-chromosomal episome in the infected cells and… Continue reading G-quadruplex-interacting compounds alter latent DNA replication and episomal persistence of KSHV
2016 / RSC Advances
Hemocyanins are giant oxygen transport proteins of molluscs and arthropods, which display high cooperativity and a complex pattern of conformations,… Continue reading Entrapment and characterization of functional allosteric conformers of hemocyanin in sol–gel matrices
2016 / International Journal of Biological Macromolecules
PE/PPE proteins are involved in several processes during Mycobacterium tuberculosis(Mtb) infection of target cells; studying them is extremely interesting as they… Continue reading Mycobacterium tuberculosis PE9 protein has high activity binding peptides which inhibit target cell invasion
2016 / Natural Product Research
Bioassay-guided fractionation of the culture extract of Pestalotiopsis adusta, an endophytic fungus isolated from the medicinal plant Clerodendrum canescens, led to the… Continue reading A new bioactive diterpenoid frompestalotiopsis adusta, an endophytic fungus from clerodendrum canescens
2016 / Journal of Bioscience and Bioengineering
Citrus plants are world widely cultivated as horticultural tree crops, and nowadays their pharmacological activities have been well studied. Since research… Continue reading Isolation and characterization of wound-induced compounds from the leaves of Citrus hassaku
2016 / Organic and Biomolecular Chemistry
G-quadruplex structures formed by oligodeoxyribonucleotides TGGUNH2GGT (AM, UNH2 = 5-amino-2′-deoxyuridine), TGGUBrGGT (BR, UBr = 5-bromo-2′-deoxyuridine) and TGGTGGT (TH) have been investigated through… Continue reading A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures
2016 / Biochemical and Biophysical Research Communications
Ubiquitination is one of the most important post-translational modifications of proteins and is involved in various cellular activities, such as… Continue reading Proteasomal degradation of damaged polyubiquitin
2016 / Scientific Reports
Thaumatin is an intensely sweet-tasting protein that elicits sweet taste at a concentration of 50 nM, a value 100,000 times larger… Continue reading A Hypersweet Protein: Removal of The Specific Negative Charge at Asp21 Enhances Thaumatin Sweetness
2016 / Neuropeptides
Huntington’s disease (HD) is recognized as a currently incurable, inherited neurodegenerative disorder caused by the accumulation of misfolded polyglutamine (polyQ)… Continue reading Self-assembly and sequence length dependence on nanofibrils of polyglutamine peptides
2016 / Materials Science and Engineering: C
Electrospun nanofibers are attractive candidates for neural regeneration due to similarity to the extracellular matrix. Several synthetic polymers have been… Continue reading PLGA nanofibers blended with designer self-assembling peptides for peripheral neural regeneration
2016 / Journal of Pharmaceutical Sciences
The purpose of this study was to develop and characterize a sodium hyaluronate microparticle-based sustained release formulation of recombinant human… Continue reading Development and Characterization of Sodium Hyaluronate Microparticle-Based Sustained Release Formulation of Recombinant Human Growth Hormone Prepared
2016 / Tetrahedron
Six new compounds, including three acremonidins F–H (1, 3, and 5), two acremoxanthones F–G (7 and 8), and acremonoxide (10), along with eight known… Continue reading Acremonidins F–H and acremoxanthones F–G, antimicrobial substances from the insect fungus Verticillium sp. BCC33181
2016 / Bioorganic and Medicinal Chemistry
Artificial chlorophyll–peptide complexes were prepared by mixing ionic chlorophyll derivatives and oligopeptides in aqueous media containing a small amount of… Continue reading Assemblies of ionic zinc chlorins assisted by water-soluble polypeptides
2016 / FEBS Letters
Many age-related neurodegenerative diseases, including Alzheimer Disease (AD), are elicited by an interplay of genetic, environmental, and dietary factors. Food… Continue reading Preferential interaction of the Alzheimer peptide Aβ‐(1‐42) with Omega‐3 containing lipid bilayers: structure and interaction studies
