2020 / Journal of Physical Chemistry B
Insulin, a simple polypeptide hormone with huge biological importance, has long been known to self-assemble in vitro and form amyloid-like… Continue reading Molecular Details of a Salt Bridge and Its Role in Insulin Fibrillation by NMR and Raman Spectroscopic Analysis
2020 / Scientific Reports
The yeast fatty acid synthase (FAS) is a barrel-shaped 2.6 MDa complex. Upon barrel-formation, two multidomain subunits, each more than… Continue reading Analysis of the co-translational assembly of the fungal fatty acid synthase (FAS)
2020 / Nature Communications
Alzheimer’s disease (AD) is characterized by amyloid plaques and progressive cerebral atrophy. Here, we report FAM222A as a putative brain atrophy susceptibility… Continue reading FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease
2020 / SN Applied Sciences
Cyanine dye or porphyrin are part of an important family of fluorophores, which have been widely used for photosensitization and… Continue reading Chiral stacking of cyanine or porphyrin as cationic fluorescent dyes in the presence of anionic polysaccharide of hyaluronic acid
2020 / Scientific Reports
Myoglobin is a heme-protein in the muscle of vertebrates with important functions in the oxygenation of tissues and as a… Continue reading Plant based production of myoglobin – a novel source of the muscle heme-protein
2020 / RSC Advances
A cyclic tri-β-peptide cyclo(β-Ala-β-Ala-β-Lys) having diethylaminonaphthalimide at the β-Lys side chain (CP3Npi) self-assembled into a peptide nanotube in a solution… Continue reading Engineering pH-responsive switching of donor–π–acceptor chromophore alignments along a peptide nanotube scaffold
2020 / Nanomaterials
Clusters of superparamagnetic iron oxide nanoparticles (SPIONs) have been incorporated into the hydrophobic core of polyethylene glycol (PEG)-modified phospholipid micelles.… Continue reading Influence of Magnetic Micelles on Assembly and Deposition of Porphyrin J-Aggregates
2020 / Pharmaceutics
Poly-aromatic peptide sequences are able to self-assemble into a variety of supramolecular aggregates such as fibers, hydrogels, and tree-like multi-branched… Continue reading Peptide-Based Soft Hydrogels Modified with Gadolinium Complexes as MRI Contrast Agents
2020 / Journal of Physical Chemistry Letters
Understanding nanoscale protein conformational changes at solid–liquid interfaces is critical for predicting how proteins will impact the performance of biomaterials… Continue reading Nanoscale Surface-Induced Unfolding of Single Fibronectin Is Restricted by Serum Albumin Crowding
2020 / Inorganic Chemistry
The crystal structure of ZnZnuA from Escherichia coli reveals two metal binding sites. (i) The primary binding site, His143, is located close… Continue reading Metal Complexes of Two Specific Regions of ZnuA, a Periplasmic Zinc(II) Transporter from Escherichia coli
2020 / International Journal of Biological Macromolecules
In this study, we report how similarly two serum albumins (bovine serum albumin (BSA) and human serum albumin (HSA)) respond… Continue reading How does cholinium cation surpass tetraethylammonium cation in amino acid-based ionic liquids for thermal and structural stability of serum albumins?
2020 / Food Chemistry
Five major proteins from egg white were separated using a successive extraction/precipitation protocol. The yield and purity of the separated… Continue reading An easy and rapid separation method for five major proteins from egg white: Successive extraction and MALDI-TOF-MS identification
2020 / Microbial Cell Factories
Therapeutic glycoproteins have occupied an extremely important position in the market of biopharmaceuticals. N-Glycosylation of protein drugs facilitates them to… Continue reading Homogeneous production and characterization of recombinant N-GlcNAc-protein in Pichia pastoris
2020 / Materials Chemistry and Physics
Immobilizing enzymes on biomimicking monolayer ultrathin films of phospholipids exhibit enhanced enzymatic activities (EAs) useful for biosensing applications. Preparation of… Continue reading Sustained and improved enzymatic activity of trypsin immobilized in the Langmuir Blodgett film of DPPC: A rapid enzyme sensor for the detection of Azocasein
2020 / Bioorganic Chemistry
The investigation of conformational features of regions of amyloidogenic proteins are of great interest to deepen the structural changes and… Continue reading Engineered β-hairpin scaffolds from human prion protein regions: Structural and functional investigations of aggregates
2020 / Langmuir
Spectroscopic analyses reveal that acridone (AD) penetrates through the structure and enters the hydrophobic cavity of the protein β-lactoglobulin (βLG).… Continue reading Probing the Hydrogen Bond Involving Acridone Trapped in a Hydrophobic Biological Nanocavity: Integrated Spectroscopic and Docking Analyses
2020 / Chinese Journal of Natural Medicines
Purpurolides D–F (1–3), three new polyoxygenated bergamotanes bearing a 6/4/5/5 tetracyclic ring system, were isolated from the endophytic fungus Penicillium purpurogenum IMM… Continue reading Three new polyoxygenated bergamotanes from the endophytic fungus Penicillium purpurogenum IMM 003 and their inhibitory activity against pancreatic lipase
2020 / Scientific Reports
In the light of promising potency of selenium nanoparticles in biomedical applications, this is the first study to report the… Continue reading Synthesis and Characterization of Selenium Nanoparticles-Lysozyme Nanohybrid System with Synergistic Antibacterial Properties
2020 / molecules
Four recombinant (r) allergens (rAmb a 8.0101, rArt v 4.0101, rBet v 2.0101, and rPhl p 12.0101) were successfully produced… Continue reading Production and Use of Recombinant Profilins Amb a 8, Art v 4, Bet v 2, and Phl p 12 for Allergenic Sensitization Studies
2020 / Journal of Natural Products
The reported fumiquinazoline-related alkaloids cottoquinazolines E–G (1–3) were reisolated from solid cultures of the fungus Neosartorya fischeri, which was isolated from… Continue reading Reisolation and Configurational Reinvestigation of Cottoquinazolines E–G from an Arthropod-Derived Strain of the Fungus Neosartorya fischeri
