2021 / Scientific Report
We developed a novel method for production of no-carrier-added (n.c.a.) [188, 189, 191Pt]PtIICl42− from an Ir target material, and then… Continue reading Synthesis of no-carrier-added [188, 189, 191Pt]cisplatin from a cyclotron produced 188, 189, 191PtCl42− complexcompound
2021 / Scientific Report
Two-pore channel 2 (TPC2) resides in endolysosomal membranes but also in lysosome-related organelles such as the melanin producing melanosomes. Gain-of-function… Continue reading Flavonoids increase melanin production and reduce proliferation, migration and invasion of melanoma cells by blocking endolysosomal/melanosomal TPC2
2021 / MDPI
In this work, the use of fluorescent molecular rotors such as 9-(2,2-dicyanovinyl)julolidine (DCVJ) and 2,3-bis(4-(phenyl(4-(1,2,2-triphenylvinyl) phenyl)amino)phenyl)fumaronitrile (TPETPAFN) was proposed for… Continue reading Molecular Rotors with Aggregation-Induced Emission (AIE) as Fluorescent Probes for the Control of Polyurethane Synthesis
2021 / Nature Communications, 12, Article number: 1530 (2021)
De novo protein design is advancing rapidly. However, most designs are for single states. Here we report a de novo… Continue reading Structural resolution of switchable states of a de novo peptide assembly
2021 / Nature Communications
The design of efficient chiral catalysts is of crucial importance since it allows generating enantiomerically pure compounds. Tremendous efforts have… Continue reading Nanoengineered chiral Pt-Ir alloys for high-performance enantioselective electrosynthesis
2021 / Translational Psychiatry
d-Serine acts as a co-agonist of N-methyl-d-aspartate receptors (NMDAR) which appear overactivated in AD, while d-aspartate is a modulatory molecule… Continue reading Serum d-serine levels are altered in early phases of Alzheimer’s disease: towards a precocious biomarker
2021 / Bioscience, Biotechnology, and Biochemistry
Corydalis ambigua (Japanese name, Ezoengosaku) flowers bloom with blue to purplish petals in early spring in Hokkaido prefecture. In this… Continue reading Blue flower coloration of Corydalis ambigua requires ferric ion and kaempferol glycoside
2020 / Scientific Reports
Peptides provide a framework for generating functional biopolymers. In this study, the pH-dependent structural changes in the 21–29 fragment peptide… Continue reading pH-controlled stacking direction of the β-strands in peptide fibrils
2020 / Nature Communications
A key feature that differentiates prokaryotic cells from eukaryotes is the absence of an intracellular membrane surrounding the chromosomal DNA.… Continue reading Isolation of a member of the candidate phylum ‘Atribacteria’ reveals a unique cell membrane structure
2020 / Nature Communications
Gramicidin A (1) is a peptide antibiotic that disrupts the transmembrane ion concentration gradient by forming an ion channel in… Continue reading Discovery of gramicidin A analogues with altered activities by multidimensional screening of a one-bead-one-compound library
2020 / Scientific Reports
The use of Target activation-induced cytidine deaminase (Target-AID) base-editing technology with the CRISPR-Cas 9 system fused with activation-induced cytidine deaminase… Continue reading Multiple gene substitution by Target-AID base-editing technology in tomato
2020 / Nature Communications volume 11, Article number: 4562 (2020)
Symmetry breaking and amplification processes have likely played a fundamental role in the development of homochirality on earth. Such processes… Continue reading Amplification of enantiomeric excess by dynamic inversion of enantiomers in deracemization of Au38 clusters
2020 / Scientific Reports volume 10, Article number: 14657 (2020)
Cystathionine β-synthase (CBS) catalyzes the condensation of serine and homocysteine to water and cystathionine, which is then hydrolyzed to cysteine,… Continue reading Cystathionine β-synthase is involved in cysteine biosynthesis and H2S generation in Toxoplasma gondii
2020 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Volume 241, 5 November 2020, 118645
Beer-Lambert-Bouguer law is for a limiting case and, therefore, it is not useful to describe the relationship between absorption signal… Continue reading Simultaneous absorption of UV–vis and circular dichroism to measure enantiomeric concentrations of praziquantel under nonlinear conditions
2017 / Science Advances
Although previous studies have attempted to create “electronics-free” insulin delivery systems using glucose oxidase and sugar-binding lectins as a glucose-sensing… Continue reading Synthetic “smart gel” provides glucose-responsive insulin delivery in diabetic mice
2018 / Scientific Reports volume 8, Article number: 4433 (2018)
Over 12% of the world’s health resources are spent on treating diabetes, as high blood glucose is the third cause… Continue reading Size Exclusion Chromatography Method for Purification of Nicotinamide Mononucleotide (NMN) from Bacterial Cells
2020 / Nature Communications volume 11, Article number: 3944 (2020)
Triacylglycerols (TG) are synthesized at the endoplasmic reticulum (ER) bilayer and packaged into organelles called lipid droplets (LDs). LDs are… Continue reading Triacylglycerols sequester monotopic membrane proteins to lipid droplets
2020 / Scientific Reports volume 10, Article number: 11845 (2020)
Human milk oligosaccharides (HMOs) are a mixture of structurally diverse carbohydrates that contribute to shape a healthy gut microbiota composition.… Continue reading Human milk and mucosa-associated disaccharides impact on cultured infant fecal microbiota
2020 / Communications Chemistry volume 3, Article number: 111 (2020)
Detection of nucleic acids is crucial to the study of their basic properties and consequently to applying this knowledge to… Continue reading Optical and theoretical study of strand recognition by nucleic acid probes
2020 / Journal of Materials and Environmental Sciences, J. Mater. Environ. Sci., 2020, Volume 11, Issue 1, Page 79-84
The fruits of Pistacia lentiscus are a source of a fixed oil used in some forested areas for culinary purposes… Continue reading Identification and quantitation of tocopherols, carotenoids and triglycerides in edible Pistacia lentiscus oil from Tunisia
