KnowledgeBase Articles Archive

Investigation of binding behaviour of procainamide hydrochloride with human serum albumin using synchronous, 3D fluorescence and circular dichroism

2016 / Journal of Pharmaceutical Analysis

Procainamide hydrochloride (PAH) interaction with human serum albumin (HSA) is of great significance in understanding the pharmacokinetic and pharmacodynamic mechanisms… Continue reading Investigation of binding behaviour of procainamide hydrochloride with human serum albumin using synchronous, 3D fluorescence and circular dichroism

Crystal structures of an archaeal Thymidylate kinase from Sulfolobus tokodaii provide insights into the role of a conserved active site Arginine residue

2016 / Journal of Structural Biology

Thymidylate kinase (TMK) is a key enzyme that plays an important role in DNA synthesis. Therefore, it serves as an… Continue reading Crystal structures of an archaeal Thymidylate kinase from Sulfolobus tokodaii provide insights into the role of a conserved active site Arginine residue

Crystal structure of Pla l 1 reveals both structural similarity and allergenic divergence within the Ole e 1-like protein family

2016 / Journal of Allergy and Clinical Immunology

Solving the structure of Pla l 1 elucidated the preserved fold of Ole e 1-like proteins while IgE cross- 33… Continue reading Crystal structure of Pla l 1 reveals both structural similarity and allergenic divergence within the Ole e 1-like protein family

Accurate quantitation for in vitro refolding of single domain antibody fra-gments expressed as inclusion bodies by referring the concomitant expression of a soluble form in the periplasms of Escherichia coli

2016 / Journal of Immunological Methods

Single domain antibody fragments from two species, a camel VHH (PM1) and a shark VNAR (A6), were derived from inclusion bodies… Continue reading Accurate quantitation for in vitro refolding of single domain antibody fra-gments expressed as inclusion bodies by referring the concomitant expression of a soluble form in the periplasms of Escherichia coli

Synthesis of monovinyl- and divinyl-chlorophyll analogs and their physical properties

2016 / Tetrahedron

Chlorophyll-a was chemically modified to methyl pyropheophorbides-a possessing 3,8-diethyl, 3-vinyl-8-ethyl, 3-ethyl-8-vinyl, and 3,8-divinyl groups. Analogous 3-ethyl-7-vinyl- and 3,7-divinyl-chlorins were prepared by derivatization… Continue reading Synthesis of monovinyl- and divinyl-chlorophyll analogs and their physical properties

RANKL Release from Self-assembling Nanofiber Hydrogels for Inducing Osteoclastogenesis In-Vitro

2016 / Acta Biomaterialia

To develop a nanofiber hydrogel (NF-hydrogel) for sustained and controlled release of the recombinant receptor activator of NF-kB ligand; (RANKL)… Continue reading RANKL Release from Self-assembling Nanofiber Hydrogels for Inducing Osteoclastogenesis In-Vitro

Ultrahigh pressure promotes colorless bovine serum albumin-glucose conjugates generation

2016 / Innovative Food Science & Emerging Technologies

Browning generation always limits the application of protein-carbohydrate conjugates. In the present study, we found that ultrahigh pressure can promote… Continue reading Ultrahigh pressure promotes colorless bovine serum albumin-glucose conjugates generation

The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme

2016 / Biophysical Journal

The conversion of human lysozyme into amyloid fibrils is associated with a rare but fatal hereditary form of nonneuropathic systemic… Continue reading The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme

Synthesis and chiroptical properties of a π-conjugated polymer containing glucose-linked biphenyl units in the main chain capable of folding into a helical conformation

2016 / Polymer Chemistry

An optically active π-conjugated polymer (poly-9) containing glucose-linked biphenyl units in the main chain was synthesized through the copolymerization of… Continue reading Synthesis and chiroptical properties of a π-conjugated polymer containing glucose-linked biphenyl units in the main chain capable of folding into a helical conformation

Different cell behaviors induced by stereochemistry on polypeptide brush grafted surfaces

2017 / Materials Chemistry Frontiers

Surface-grafted poly-γ-benzyl-glutamate brushes with different secondary structures were prepared and used to study the influence of main-chain chirality on cell… Continue reading Different cell behaviors induced by stereochemistry on polypeptide brush grafted surfaces

C-Phycocyanin as a potential biosensor for heavy metals like Hg2+ in aquatic systems

2016 / RSC Advances

The purpose of this study is to exploit the fluorescence quenching ability of C-phycocyanin (CPC) with heavy metals, establishing it… Continue reading C-Phycocyanin as a potential biosensor for heavy metals like Hg2+ in aquatic systems

The application of G-quadruplex based assay with an iridium(III) complex to arsenic ion detection and its utilization in a microfluidic chip

2016 / Journal of Materials Chemistry B

In this work, the iridium(III) complex 1 was synthesized and employed to construct an assay which is based on G-quadruplex for detecting… Continue reading The application of G-quadruplex based assay with an iridium(III) complex to arsenic ion detection and its utilization in a microfluidic chip

Interaction of anticancer drug clofarabine with human serum albumin and human α-1 acid glycoprotein. Spectroscopic and molecular docking approach

2016 / Journal of Pharmaceutical and Biomedical Analysis

The binding interaction between clofarabine, an important anticancer drug and two important carrier proteins found abundantly in human plasma, Human… Continue reading Interaction of anticancer drug clofarabine with human serum albumin and human α-1 acid glycoprotein. Spectroscopic and molecular docking approach

Attenuation of amyloid fibrillation in presence of Warfarin: A biophysical investigation

2016 / International Journal of Biological Macromolecules

Protein misfolding and aggregation are associated with more than twenty diseases, such as neurodegenerative diseases. The amyloid oligomers and fibrils… Continue reading Attenuation of amyloid fibrillation in presence of Warfarin: A biophysical investigation

Differential copper binding to Alpha-synuclein and its disease-associated mutants affect the aggregation and amyloid formation

2016 / Biochimica et Biophysica Acta (BBA) - General Subjects

Copper is an essential trace element required for the proper functioning of various enzymes present in central nervous system. An… Continue reading Differential copper binding to Alpha-synuclein and its disease-associated mutants affect the aggregation and amyloid formation

Insight into the biochemical, kinetic and spectroscopic characterization of garlic (Allium sativum) phytocystatin: Implication for cardiovascular disease.

2016 / International Journal of Biological Macromolecules

Phytocystatins are cysteine proteinase inhibitors present in plants. They play crucial role in maintaining protease-anti protease balance and are involved… Continue reading Insight into the biochemical, kinetic and spectroscopic characterization of garlic (Allium sativum) phytocystatin: Implication for cardiovascular disease.

Chemically modified cellulose strips with pyridoxal conjugated red fluorescent gold nanoclusters for nanomolar detection of mercuric ions

2016 / Biosensors and Bioelectronics

One-pot approach was adopted for the synthesis of highly luminescent near-infrared (NIR)-emitting gold nanoclusters (AuNCs) using bovine serum albumin (BSA)… Continue reading Chemically modified cellulose strips with pyridoxal conjugated red fluorescent gold nanoclusters for nanomolar detection of mercuric ions

Synthesis and Label Free Characterization of a Bimolecular PNA Homo Quadruplex

2016 / Biochimica et Biophysica Acta (BBA) - General Subjects

G-quadruplex DNA is involved in many physiological and pathological processes. Both clinical and experimental studies on DNA G-quadruplexes are slowed… Continue reading Synthesis and Label Free Characterization of a Bimolecular PNA Homo Quadruplex

Limited changes in physical and rheological properties of peroxidase-cross-linked apo-α-lactalbumin after heat treatment

2016 / Food Hydrocolloids

The current study aims at elucidating the effect of heating on the physical properties of peroxidase-cross-linked (apo) α-lactalbumin (α-LA) aggregates with… Continue reading Limited changes in physical and rheological properties of peroxidase-cross-linked apo-α-lactalbumin after heat treatment

Properties and separation method of enantiomers of the mono- and bis-substituted derivatives of 3,3′,4,4′-tetramethyl-1,1′-diphosphaferrocene: structural analysis using X-ray diffraction and circular dichroism

2016 / Tetrahedron: Asymmetry

This work expands on the recent separation of the enantiomers of the C2-symmetrical bis-substituted derivatives of 1,1′-diphosphaferrocene. The effective separation of… Continue reading Properties and separation method of enantiomers of the mono- and bis-substituted derivatives of 3,3′,4,4′-tetramethyl-1,1′-diphosphaferrocene: structural analysis using X-ray diffraction and circular dichroism

JASCO

KnowledgeBase Articles

Year

Technique

Industry