Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The novel Synchrotron Radiation Circular Dichroism (SRCD) technique is becoming a new tool of investigation for the molecular structures of… Continue reading New Synchrotron Radiation Circular Dichroism end-station on DISCO beamline at SOLEIL synchrotron for biomolecular analysis
Leah Pandiscia, PhD
July 28, 2017
Acetohydroxy acid synthase (AHAS) and related enzymes catalyze the production of chiral compounds [(S)-acetolactate, (S)-acetohydroxybutyrate, or (R)-phenylacetylcarbinol] from achiral substrates… Continue reading Monitoring the acetohydroxy acid synthase reaction and related carboligations by circular dichroism spectroscopy
Leah Pandiscia, PhD
July 28, 2017
The chiroptical properties of nonanuclear Tb(III) clusters are reported. The nonanuclear Tb(III) clusters are composed of nine Tb(III) ions, ten… Continue reading Chiroptical Properties of Nonanuclear Tb(III) Clusters with Chiral Champhor Derivative Ligands
Leah Pandiscia, PhD
May 24, 2018
Two allene derivatives, l- and d-N-(1-(octylamino)-1-oxopropan-2-yl)-4-(propa-1,2-dien-1-yloxy)benzamide (l-1 and d-1), bearing chiral amide pendants were designed and synthesized. Living polymerizations of l-1 and d-1 with allylnickel complex as a… Continue reading Synthesis and Chiroptical Properties of Helical Polyallenes Bearing Chiral Amide Pendants
Leah Pandiscia, PhD
July 28, 2017
Human cystatin C (HCC), encoded by cystatin 3 gene, is a 13.3 kDa endogenous cysteine proteinase inhibitor and an important biomarker… Continue reading Efficient expression, purification and characterization of native human cystatin C in Escherichia coli periplasm
Leah Pandiscia, PhD
July 28, 2017
Nanoparticles (XG/Ly NPs) were fabricated by like charged xanthan gum and lysozyme and the interactions between them in the preparation… Continue reading Synthesis and characterization of nanoparticles based on negatively charged xanthan gum and lysozyme
Leah Pandiscia, PhD
July 28, 2017
Unsymmetrical vesicular membranes were prepared from a binary mixture of the A3B-type and the AB-type host polypeptides, which were composed… Continue reading Facile and Precise Formation of Unsymmetric Vesicles Using the Helix Dipole, Stereocomplex, and Steric Effects of Peptides
Leah Pandiscia, PhD
July 28, 2017
The interaction of cis-DDP and trans-DDP (DDP = [PtCl2(NH3)2]) with the C-terminal zinc finger (ZF2) of the HIVNCp7 nucleocapsid protein was investigated by fluorescence,… Continue reading The reaction of dichlorodiammineplatinum(II), [PtCl2(NH3)2], isomers with zinc fingers
Leah Pandiscia, PhD
July 28, 2017
Among the various chiroptical spectroscopic methods circular dichroism (CD), optical rotatory dispersion (ORD), Raman optical activity (ROA), the methods based… Continue reading Chiroptical spectroscopic techniques based on fluorescence
Leah Pandiscia, PhD
May 24, 2018
Some of the pathological hallmarks of the Alzheimer’s disease brain are senile plaques composed of insoluble amyloid-β protein (Aβ) fibrils.… Continue reading Biophysical Comparison of Soluble Amyloid-β(1–42) Protofibrils, Oligomers, and Protofilaments
Leah Pandiscia, PhD
July 28, 2017
Dengue virus (DENV) infection is a growing public health threat with more than one-third of the world’s population at risk.… Continue reading Dengue virus NS4A cytoplasmic domain binding to liposomes is sensitive to membrane curvatur
Leah Pandiscia, PhD
July 28, 2017
Phosphoribulokinase (PRK) in the green alga Chlamydomonas reinhardtii is a finely regulated and well-studied enzyme of the Benson–Calvin cycle. PRK can form… Continue reading Phosphoribulokinase from Chlamydomonas reinhardtii: a Benson–Calvin cycle enzyme enslaved to its cysteine residues
Leah Pandiscia, PhD
July 28, 2017
Recent advances in equipment enabled the collection of solid-state electronic circular dichroism (ECD) spectra using the commercially available integrating sphere… Continue reading Transmission vs. Diffuse Transmission in Circular Dichroism: What to Choose for Probing Solid-State Samples?
Leah Pandiscia, PhD
July 28, 2017
Transcription elongation factor NusG from Escherichia coli couples transcription and translation. It is the only conserved transcription factor in all three kingdoms… Continue reading The two domains of Mycobacterium tuberculosis NusG protein are dynamically independent
Leah Pandiscia, PhD
July 28, 2017
The first MCD spectral data for an open shell first row transition metal complex of tetraphenyltetraacenaphthoporphyrin (TPTANP) are reported. The… Continue reading Magnetic circular dichroism spectroscopy of cobalt tetraphenyltetraacenaphthoporphyrin
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Circular dichroism (CD) spectra have been measured in the range of 400–200 nm on CH3OH solutions of both enantiomers for the… Continue reading Experimental and calculated circular dichroism spectra of monoaza[5]helicenes
Leah Pandiscia, PhD
July 28, 2017