Involvement of the Lhcx protein Fcp6 of the diatom Cyclotella meneghiniana in the macro-organization and structural flexibility of thylakoid membranes

2016 / Biochimica et Biophysica Acta (BBA) - Bioenergetics

Diatoms possess special light-harvesting proteins involved in the photoprotection mechanism called non-photochemical quenching (NPQ). These Lhcx proteins were shown to… Continue reading Involvement of the Lhcx protein Fcp6 of the diatom Cyclotella meneghiniana in the macro-organization and structural flexibility of thylakoid membranes

Leah Pandiscia, PhD

Residual structures in the unfolded state of starch-binding domain of glucoamylase revealed by near-UV circular dichroism and protein engineering techniques

2016 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Protein folding is a thermodynamic process driven by energy gaps between the native and unfolded states. Although a wealth of… Continue reading Residual structures in the unfolded state of starch-binding domain of glucoamylase revealed by near-UV circular dichroism and protein engineering techniques

Leah Pandiscia, PhD

Light Scattering Analysis of Mono- and Multi-PEGylated Bovine Serum Albumin in Solution: Role of Composition on Structure and Interactions

2016 / The Journal of Physical Chemistry B

The effect of polymer conjugation on the interactions between proteins in solution is evaluated by systematic analysis of the second… Continue reading Light Scattering Analysis of Mono- and Multi-PEGylated Bovine Serum Albumin in Solution: Role of Composition on Structure and Interactions

Leah Pandiscia, PhD

Tunable Aggregation-Induced Emission of Tetraphenylethylene via Short Peptide-Directed Self-Assembly

2016 / Advanced Materials Interfaces

Tunable aggregation-induced emission of tetraphenylethylene is well realized via short peptide-directed self-assembly associated with synergy of noncovalent intermolecular interactions, including electrostatic,… Continue reading Tunable Aggregation-Induced Emission of Tetraphenylethylene via Short Peptide-Directed Self-Assembly

Leah Pandiscia, PhD

Bacteria in an intense competition for iron: Key component of the Campylobacter jejuni iron uptake system scavenges enterobactin hydrolysis product

2016 / PNAS

To acquire essential Fe(III), bacteria produce and secrete siderophores with high affinity and selectivity for Fe(III) to mediate its uptake… Continue reading Bacteria in an intense competition for iron: Key component of the Campylobacter jejuni iron uptake system scavenges enterobactin hydrolysis product

Leah Pandiscia, PhD

Alpha-synuclein and familial variants affect the chain order and the thermotropic phase behavior of anionic lipid vesicles

2016 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Alpha-synuclein (aSN) is a presynaptic protein with a pathological role in Parkinson’s disease (PD). The mutants A30P, E46K and A53T… Continue reading Alpha-synuclein and familial variants affect the chain order and the thermotropic phase behavior of anionic lipid vesicles

Leah Pandiscia, PhD

Dihydrochelerythrine and its derivatives: Synthesis and their application as potential G-quadruplex DNA stabilizing agents

2016 / Bioorganic and Medicinal Chemistry

A convenient route was envisaged toward the synthesis of dihydrochelerythrine (DHCHL), 4 by intramolecular Suzuki coupling of 2-bromo-N-(2-bromobenzyl)-naphthalen-1-amine derivative 5 via in situ generated… Continue reading Dihydrochelerythrine and its derivatives: Synthesis and their application as potential G-quadruplex DNA stabilizing agents

Leah Pandiscia, PhD

Similarity of a 16.5 kDa tegumental protein of the human liver fluke Opisthorchis viverrini to nematode cytoplasmic motility protein

2016 / Molecular and Biochemical Parasitology

Opisthorchis viverrini is the causative agent of human opisthorchiasis in Thailand and long lasting infection with the parasite has been correlated… Continue reading Similarity of a 16.5 kDa tegumental protein of the human liver fluke Opisthorchis viverrini to nematode cytoplasmic motility protein

Leah Pandiscia, PhD