2020 / Biochemistry and Biophysics Reports
Rab proteins, a family of small guanosine triphosphatases, play key roles in intracellular membrane trafficking and the regulation of various… Continue reading The dynamic structure of Rab35 is stabilized in the presence of GTP under physiological conditions
2020 / Archives of Biochemistry and Biophysics
Although the mystery molecule p53 has been studied extensively, still several unknown mechanisms need to be elucidated. Being a central… Continue reading Conformational dynamics of p53 N-terminal TAD2 region under different solvent conditions
2020 / Tetrahedron
Anti-pseudorabies virus (PRV) activity-guided isolation of an endophytic fungus Talaromyces purpureogenus resulted in seven rare polycyclic meroterpenoids talaromyolides E–K, together… Continue reading Polycyclic meroterpenoids, talaromyolides E − K for antiviral activity against pseudorabies virus from the endophytic fungus Talaromyces purpureogenus
2020 / Microbial Pathogenesis
Haemocyanin (Hc) is a non-specific innate immune protein present in the haemolymph of arthropods and molluscs. In the current study,… Continue reading Immunological and antibiofilm property of haemocyanin purified from grooved tiger shrimp (Penaeus semisulcatus): An in vitro and in silico approach
2020 / Colloids and Surfaces A: Physicochemical and Engineering Aspects
Molecules self-assembly in confined space such as in cell to form microfilaments is a crucial process to achieve special functionality.… Continue reading Thermolysin-triggered short peptides self-assembly in confined space and application in cell culturing
2020 / Langmuir
Herein we report the interaction of 3-hydroxyflavone (3HF) with various isomeric forms of Human Serum Albumin (HSA), namely, the N-isoform… Continue reading Contrasting Thermodynamics Governs the Interaction of 3-Hydroxyflavone with the N-Isoform and B-Isoform of Human Serum Albumin
2020 / Biophysical Chemistry
Intrinsically disordered proteins (IDPs) comprise ~30–40% of the proteome, have key roles in cellular processes, and have been reported to… Continue reading Disorder under stress: Role of polyol osmolytes in modulating fibrillation and aggregation of intrinsically disordered proteins
2020 / Experimenta Parasitology
Evaluation of the murine isotype antibodies is essential in subunit vaccine development because inbred mouse strains with diverse genetic backgrounds… Continue reading Measuring of IgG2c isotype instead of IgG2a in immunized C57BL/6 mice with Plasmodium vivax TRAP as a subunit vaccine candidate in order to correct interpretation of Th1 versus Th2 immune response
2020 / Analytical Chemistry
Our recent publication illustrates the critical role of phenylalanine-mediated aromatic-aromatic interactions in determining the assembly of peptidic β-sheets. However, the… Continue reading Increasing the Assembly Efficacy of Peptidic β-Sheets for a Highly-Sensitive HIV Detection
2020 / Food and Bioprocess Technology
There are many polyphenols used for the preservation of fish, but the interaction mechanism between polyphenols and fish protein is… Continue reading Studies on the Binding Interactions of Grass Carp (Ctenopharyngodon idella) Myosin with Chlorogenic Acid and Rosmarinic Acid
2020 / International Journal of Biological Macromolecules
Findings small molecules with protein disaggregation effects are lately needed. For the first time, we studied the in vitro-antifibrillogenic effects of… Continue reading Cyanidin 3-rutinoside defibrillated bovine serum albumin under the glycation-promoting conditions: A study with multispectral, microstructural, and computational analysis
2020 / FASEB BioAdvances
Calmodulin (CaM), the key calcium sensor of eukaryotic cells regulating a great number of target proteins, belongs to the most… Continue reading Comparison of Ligand Binding and Conformational Stability of Human Calmodulin with its Homologue from the Malaria Parasite Plasmodium falciparum
2020 / Ecotoxicology and Environmental Safety
An increasing amount of Fluoranthene (Fla) and Benz(a)anthracene (BaA) is being produced and used, eventually entering the soil sediments. The… Continue reading Toxicity assessment of Fluoranthene, Benz(a)anthracene and its mixed pollution in soil: Studies at the molecular and animal levels
2020 / Food Chemistry
In the present study, effects of riboflavin (RF) and kelp polyphenol extracts (KPE) on mackerel (Scomberomorus Niphonius) myofibrillar protein (MP)… Continue reading The dual effects of riboflavin and kelp polyphenol extracts on the gel properties of myofibrillar protein from Scomberomorus Niphonius under UVA irradiation
2020 / International Journal of Biological Macromolecules
One popular and relevant proposed function for cyanobacterial hemoglobin (Synechocystis Hb) is anaerobic nitrite reductase in vivo. During such reduction reactions, the… Continue reading Identification and characterization of a recombinant cognate hemoglobin reductase from Synechocystis sp. PCC 6803
2020 / Journal of Molecular Structure
In an attempt to overcome limitations of Curcumin from being an important molecule in biology and medicine, a monomeric complex… Continue reading Spectroscopy driven DFT computation for a structure of the monomeric Cu2+-Curcumin complex and thermodynamics driven evaluation of its binding to DNA: Pseudo-binding of Curcumin to DNA
2020 / Macromolecular Chemistry and Physics
Thermoresponsive polypeptides bearing amide pendants with an upper critical solution temperature (UCST) under physiologically relevant solution conditions are developed. A… Continue reading Preparation and Properties of UCST‐Type Thermoresponsive Polypeptide Bearing Amide Pendants
2020 / Colloids and Surfaces B: Biointerfaces
Binding effect and interaction of 2-pentadecanoyloxymethyl)trimethylammonium bromide (DMGM-14) with bovine serum albumin (BSA) and hen egg white lysozyme (HEWL) were… Continue reading Investigating the biomolecular interactions between model proteins and glycine betaine surfactant with reference to the stabilization of emulsions and antimicrobial properties
2020 / Fitoterapia
Hookerianones A – E (1–5), five new polyprenylated acylphloroglucinols (PPAPs), along with six known ones, were isolated from the aerial… Continue reading Polyprenylated acylphloroglucinols as deubiquitinating protease USP7 inhibitors from Hypericum hookerianum
2020 / RSC Advances
Artemisinin (ART) and its biogenetic precursors artemisinic acid (AA) and dihydroartemisinic acid (DHAA) are important traditional medicinal herb compounds with… Continue reading Comparative in vitro cytotoxicity and binding investigation of artemisinin and its biogenetic precursors with ctDNA
